Schmidt's Nurseries is easily accessible from all major highways. 

From Philadelphia:
Follow Rt. 152 North to the Nursery entrance on your left just before Susquehanna Rd.

From the PA Turnpike (Ft. Washington Exit):
Follow Rt. 309 South to the first exit (Oreland).  This puts you on Pennsylvania Avenue.  Follow to second light and turn left (Camphill Road).  Follow to the first right (Dreshertown Road).  Follow Dreshertown Rd. until it ends at Limekiln Pike (Rt. 152) and turn left.  The Nursery is about 300 yards on the left just before Susquahanna Rd.